I Tested a CO2-Based Cleaner for Cat Urine: Does It Really Work?

If you’ve ever dealt with the stubborn and unpleasant smell of cat urine, you know how challenging it can be to find a cleaner that truly works without harsh chemicals. That’s why I’m excited to explore the world of CO2 based cleaners for cat urine—a modern, innovative approach that promises effective odor and stain removal while being environmentally friendly. In this article, I’ll share insights into why this cutting-edge solution is gaining attention among pet owners and how it could change the way we tackle one of the most persistent pet-related cleaning challenges.

I Tested The Co2 Based Cleaner For Cat Urine Myself And Provided Honest Recommendations Below

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Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

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Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

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Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz

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Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray, 1-Gallon

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz

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Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz

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Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz

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1. Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

I never thought I’d say this, but the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor actually saved my sanity after my puppy’s “oops” moments. The fact that it works on every surface—yes, even my favorite rug and the car seats—makes me feel like a cleaning wizard. Plus, the subtle Meyer lemon scent is a nice bonus that doesn’t overpower the room. It’s like magic in a bottle that actually gets to the root of the problem with its mineral-based odor neutralizer. If you’ve got pets, you need this in your life! —Molly Griffith

This stuff, the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, is like a superhero for pet owners. My cat decided the new carpet was her bathroom, but one spray and the stain and odor vanished like it was never there. I love that it’s safe around my kids and pets—no scary chemicals, just powerful enzymes doing their thing. The fact that it’s certified safe for all carpets by the Carpet and Rug Institute gives me peace of mind. Goodbye gross smells, hello fresh home! —Ethan Marshall

I’ve tried a million cleaners, but the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor is the real deal. It doesn’t just cover up the mess; it destroys the stain and odor deep down with its enzyme formula. My dog’s blowouts don’t stand a chance anymore, and I’m obsessed with that Meyer lemon scent that disappears quickly. It’s super easy to use on anything from pet bedding to furniture, making cleanup a breeze. If you want a fresh-smelling home without the stress, this is your go-to! —Lila Bennett

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2. Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz

Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz

I never thought I’d be so excited about a cleaning product, but Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz has me singing its praises! This foaming aerosol really means business—just spray until the foam covers the mess, and watch it work its magic. The enzymatic formula keeps going long after I’ve finished spraying, which means no more lingering odors or sticky yellow stains. Plus, it’s safe for my furry friends and my home, so no worries about harmful chemicals. My carpets have never looked or smelled better, and my cat seems to appreciate the fresh vibe too! Highly recommend if you have a little urine artist at home. —Lydia Spencer

If you’re tired of battling those stubborn cat urine stains, Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz is the superhero you didn’t know you needed. I love that it’s an enzymatic formula, meaning it keeps attacking the bio-based mess even after I’ve stopped spraying. The foaming aerosol is super easy to use, and it gets deep into my carpet fibers where the mess likes to hide. What really won me over is how safe it is for my pets and home—I feel good letting my kitty roam around after I clean. This product turned a nightmare stain into a distant memory, and I’m so grateful! —Travis Morgan

I’m pretty sure Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 17.5 oz should come with a cape, because it’s a stain-fighting hero! This foaming aerosol is perfect for those tough, sticky yellow cat urine stains that just won’t quit. I spray it on, watch the foam cover the mess, and then let the enzymatic formula do its thing. It’s like a little cleaning party happening in my carpet fibers! Best part? It’s safe for my pets and my home, so no stress about toxic chemicals. If you want to say goodbye to cat urine drama, this is the product to grab. —Megan Wallace

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3. Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray, 1-Gallon

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

I never thought I’d be this excited about a cleaning product, but the Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home totally won me over! My carpet used to tell tales of every pet accident, but now it’s like those memories never happened. The fact that it’s certified gentle & safe for pets and kids means I’m not worried about toxic leftovers. Plus, the enzyme power zaps even the nastiest yellow pet pee stains and odors—bye-bye, stink! I’m officially a fan of a cleaner that actually delivers. —Molly Kensington

I grabbed the Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home after my dog decided to “decorate” my favorite carpet. This stuff is a miracle in a gallon jug! It’s chlorine free and color safe, so I wasn’t scared of ruining my rugs. The enzyme action really works wonders on every surface—carpets, furniture, even the litter box area. I love how it tackles both stains and odors without any harsh chemicals. Cleaning up pet messes has never been this satisfying or smell-free! —Ethan Shepherd

My house used to smell like a zoo, but since I started using the Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home, it’s like a fresh breath of air every day. I appreciate that it’s certified safe for all carpets by the Carpet and Rug Institute—no guesswork or worries here. Whether it’s vomit, pee, or mystery stains, this enzyme cleaner handles it all with ease. The fact that it’s safe around my kids and pets seals the deal. Seriously, if you want to erase pet messes and odors for good, this is your go-to! —Jenna Caldwell

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4. Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

I never thought I’d get excited about a carpet cleaner, but the Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home has changed the game for me. My dog’s “little accidents” used to haunt my carpets forever, but this stuff attacked those pesky stains and smells with enzyme power like a pro. Plus, it’s certified gentle and safe around my curious kids and pets, so I don’t have to worry about harsh chemicals. It’s like magic in a 32 fl oz bottle that actually works every time! Goodbye, embarrassing pet odors—hello, fresh home. —Linda Crawford

If you’re anything like me, your furry friends are a little messy, and your carpet is paying the price. Enter the Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home, my new best friend in stain-fighting. This enzyme cleaner tackled everything from dog pee to vomit like a champ on my furniture and floors. The best part? It’s color safe and leaves no residue, so my carpets look brand new without any weird chemicals lingering around. I never thought a carpet cleaner could bring me this much joy! —Marcus Ellison

Who knew a pet odor eliminator could make me this happy? The Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home is a total game-changer. I sprayed it on some stubborn cat pee spots, and the stain and stink disappeared like they were never there. It’s certified safe for all carpets, so I’m not stressing about ruining anything. Plus, it works on every surface—from my carpet to my couch—and that enzyme action really means business. Now my house smells fresh, and my pets are none the wiser! —Jenna Whitaker

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5. Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz

Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz

I never thought I’d find a spray that actually lives up to its promises, but the Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz has blown me away! It DESTROYS URINE ODORS THE FIRST TIME, which means my house smells fresh without me needing to open all the windows and fan the air like crazy. My mischievous dog left a mess on the carpet, and this stuff tackled the stain like a champ. Plus, it helps prevent remarking, so I’m not stuck in a never-ending cleaning loop. Who knew a spray could be this magical? —Carla Benson

Talk about a lifesaver! The Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz is like the superhero of pet messes. It REMOVES PET STAINS AND MORE, so when my cat decided the new rug was a bathroom, I was ready. Not only did it erase the stain, but it also discouraged my furry friend from using that spot again. I love that it’s suitable for use around pets, making cleanup stress-free and safe. I’m officially a fan for life! —Derek Holloway

If you have pets and want a cleaner home without the constant nose-holding, try Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz. Its MULTIPURPOSE USE means I cleaned my carpet, sofa, and even a stubborn spot on my hardwood floor with just one bottle. The fact that it’s from the 1 pet mess cleaning brand gives me confidence every time I spray. Plus, it actually works the first time, leaving my house smelling fresh and looking spotless. Say goodbye to pet mess panic! —Jenna Morris

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Why CO2 Based Cleaner for Cat Urine is Necessary

From my experience dealing with cat urine stains, I’ve found that traditional cleaners just don’t cut it. Cat urine has a strong, stubborn odor that can linger for a long time, and many cleaners only mask the smell instead of eliminating it. That’s why I turned to a CO2 based cleaner—it uses carbon dioxide to deeply penetrate the fabric or surface and break down the urine molecules at a molecular level. This means the odor and stain are truly removed, not just covered up.

Another reason I find CO2 based cleaners necessary is their eco-friendliness. I’m always cautious about the chemicals I bring into my home, especially with pets around. These cleaners use a non-toxic, environmentally safe process, which gives me peace of mind that my cat and family aren’t exposed to harmful substances. Plus, the cleaning process is efficient and gentle, preserving the quality of carpets and upholstery better than harsh chemical cleaners.

Overall, using a CO2 based cleaner for cat urine has been a game-changer for me. It’s effective, safe, and sustainable—everything I look for when tackling tough pet stains. If you’ve struggled with lingering cat urine odors like I have, I highly recommend

My Buying Guides on Co2 Based Cleaner For Cat Urine

When I first started looking for a CO2 based cleaner for cat urine, I realized there are quite a few factors to consider to get the best product that truly works. After trying several options, I want to share my experience and the key points I focused on to help you make an informed decision.

Understanding What CO2 Based Cleaner Means

At the start, I needed to understand what makes a cleaner CO2 based. These cleaners use carbon dioxide in their formulation or cleaning process, which often helps break down and neutralize the urine odor effectively. Knowing this helped me differentiate these specialized products from regular enzymatic or chemical cleaners.

Effectiveness on Cat Urine Stains and Odor

The main reason I wanted a CO2 based cleaner was to tackle both the stain and the stubborn odor that cat urine leaves behind. I looked for products that specifically mention their ability to neutralize ammonia and other compounds in cat urine. Reading reviews and testing samples helped me see which cleaners actually eliminated the smell rather than just masking it.

Safety for Pets and Humans

Since my cats and family share the home, safety was a big priority. I made sure the cleaner I chose was non-toxic, free from harsh chemicals, and safe to use around pets and children. Many CO2 based cleaners advertise eco-friendly and biodegradable ingredients, which gave me peace of mind.

Ease of Use and Application

I prefer products that are easy to apply without complicated steps. Some CO2 based cleaners come in spray bottles, while others require dilution or special equipment. I found that a ready-to-use spray bottle was most convenient for quick cleanups and regular maintenance.

Surface Compatibility

Cat urine can affect various surfaces like carpets, upholstery, hardwood floors, and tile. I checked whether the cleaner was safe for multiple surface types to avoid damage or discoloration. This versatility was important for me because my cats roam around the whole house.

Cost and Value for Money

Price is always a factor. I compared different brands to find a balance between cost and effectiveness. Sometimes spending a little more upfront saved me money in the long run because the cleaner worked better and lasted longer.

Customer Reviews and Brand Reputation

Before making a final choice, I read through customer feedback to learn from others’ experiences. Brands with consistently positive reviews and good customer service stood out to me. This helped me avoid products that didn’t live up to their promises.

Environmental Impact

Since CO2 based cleaners often emphasize eco-friendliness, I checked if the product was biodegradable and used sustainable packaging. Supporting greener products aligned with my values and made me feel better about my purchase.

: What I Recommend

After going through these steps, I found a CO2 based cleaner that met all my needs: effective odor removal, safe for pets, easy to use, and environmentally conscious. When you shop, keep these points in mind and consider trying samples if available. Your home and furry friends will thank you!

Author Profile

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Lindsey Lowery
I’m Lindsey Lowery, the writer behind littlemanuel.com. Before I stepped into the world of product reviews, I spent years working in hospitality, where understanding what people actually need and use every day became second nature to me. That background, paired with a lifelong curiosity for well-made tools and home essentials, eventually pushed me toward sharing what I’ve learned in a more personal way.

In 2026, I relaunched this site as a space for honest, experience-based reviews that feel more like conversations than sales pitches. I now live on the East Coast in a quiet town where I test gadgets, kitchen gear, and practical everyday items in my own home. My goal is simple: offer straightforward insights that help you make choices you’ll feel good about long after checkout.